Those who relapse, or whose cancer is resistant to standard chemotherapy, are treated with high-dose chemotherapy followed by an autologous transplant.Īllogeneic transplants work differently from autologous transplants. Most younger patients with this disease are cured by chemotherapy alone. Those who are not cured – who relapse after treatment – are eligible for a transplant. Patients are first treated with standard chemotherapy. Lymphoma, including Hodgkin lymphoma as well as non-Hodgkin lymphoma.Transplant is generally available to patients whose myeloma has plateaued after initial treatment and who are fit enough to tolerate high-dose chemotherapy. Multiple myeloma, in which high doses of chemotherapy followed by transplant can slow the relapse of the disease and extend patients’ survival.In adults, autologous transplants are used to treat: Autologous transplants are used for certain cancers that respond well to chemotherapy, while allogeneic transplants are generally reserved for certain cancers that are less responsive to chemotherapy but are more vulnerable to attack from the new immune system generated by the donor’s stem cells. The choice of an autologous or allogeneic transplant is based on the type of disease an individual has. Unrelated donors are identified through a registry such as the Be The Match ® registry of the National Marrow Donor Program. The stem cells are then reinfused into the body to create new, healthy blood cells and platelets.Īllogeneic transplants use stem cells from a closely matched donor, who may be related to the patient or be unrelated. ![]() The cells are collected before the patient receives high doses of chemotherapy, which kills cancer cells that survive lower doses. In adults, transplants are used to treat a range of blood-related cancers, myelodysplastic syndromes, and non-malignant blood disorders.Īutologous transplants use a patient’s own stem cells. Both allogeneic and autologous stem cell transplants involve treating a patient with chemotherapy followed by an infusion of blood-forming stem cells, with a goal of curing the cancer or extending the time before the disease relapses.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |